Using insect repellent on beehives, located in the apiary west of Catherby and in southern Seers' Village, causes the bees to leave. Using a bucket on the beehive then gives a bucket of wax, which is used in Merlin's Crystal and Troll Romance. Insect repellent must be used on the beehive every time, otherwise the bees will have returned and no wax will be collected.
Despite Insect repellent's examine text claiming that it "drives away all known 6 legged creatures", it has no effect on many 6 legged creatures, such as Cave bugs.