The large pouch is created when using the orb on a regular large pouch during the Devious Minds quest. It is used as a teleport beacon for a mysterious character later known as the Assassin to steal a relic from the Entrana church.
Unlike the original large pouch, this item will not be kept on death.
If players have already obtained the Colossal pouch from Guardians of the Rift mini-game, it can be used to hold the orb during the devious minds quest line and will not be lost after placing the orb on the altar during the quest line.